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 The Society of Interventional Oncology submitted updates to the NCCN hepatobiliary guidelines. Submitted by Gregory Nadolski, MD, Assistant Professor, University of Pennsylvania, Sid Padia, MD, Associate Professor, UCLA, and Beau Toskich, MD, Radiologist, Mayo Clinic. This letter requests the NCCN Guidelines Panel for Hepatobiliary Cancer review five specific changes and data regarding locoregional therapy for the treatment of HCC. Download the complete letter here.
 Check out the latest SIO Case Spotlight: Hepatopulmonary shunt reduction via bland embolization before Y 90 radioembozation of hepatic neuroendocrine tumor from authors Jacob Miller MD, Seza Gulec MD, Brian Baigorri MD, Roberto Fourzali MD of Aventura Hospital and Medical Center.
What is Case Spotlight? The Society of Interventional Oncology presents an opportunity to share key findings from interesting patient cases within the interventional oncology community. Access to these cases and engaging in the discussion surrounding their content is one of the benefits of SIO membership.
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The Society of Interventional Oncology (SIO) is thrilled to host the foremost national experts as faculty of SIO Master Class: Catheter Directed Therapy for the New IR/IO Practice, taking place this November.
Each speaker brings a unique perspective to this topic and attendees will have the benefit of learning from these leaders in a small group setting.
Designed for interventional radiologists and interventional oncologists, this comprehensive day-and-a-half course will feature an interactive approach to catheter directed therapies, led by the best in the field.
 Join us at the SIO Master Class to gain new insights and learn best practices through case-based discussions, presentations, and hands-on workshops. You will walk away with the skills required to handle intricate challenges facing new IR/IO practices in today’s specialized and continuously-evolving environment.
Attendees are required to make their own hotel reservation. SIO will cover the housing cost for one (1) night of room and tax for each attendee at the Raddison Blue Hotel in Chicago, Illinois, USA
Space is limited and available on a first-come, first-served basis. Register early to secure your spot.
Explore the Program and Register Now!
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OsteoCool™ indications have expanded! Learn more about treatment options for patients with painful bone metastases and benign bone tumors, such as osteoid osteoma. Learn about OsteoCool™.
Learn about OsteoCool™. |
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Theranostics
Chemoimmunotherapy is an emerging combinatorial modality for the treatment of cancers resistant to common first-line therapies, such as chemotherapy and checkpoint blockade immunotherapy. Researchers used biodegradable nanoparticles as delivery vehicles for local, slow and sustained release of doxorubicin, two immune adjuvants and one chemokine for the treatment of resistant solid tumors. READ MORE
Cancer Medicine
This study aimed to investigate the clinical significance of previous and/or concurrent application of radiotherapy (RT) in the course of nivolumab treatment for advanced hepatocellular carcinoma (HCC). Patients with advanced HCC who received nivolumab treatment between March 2017 and May 2018. were included. Nivolumab treatment was indicated in patients who did not respond to conventional therapy including locoregional therapy and/or sorafenib. RT was performed when necessary for curative/palliative purpose. READ MORE |
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Therapeutic Advances in Medical Oncology
Whether the efficient heat-generating mechanism of microwave ablation (MWA) is comparable with resection (RES) in treating hepatocellular carcinoma (HCC) remains unclear. This retrospective cohort study comprised 126 and 1183 patients with HCC meeting the Milan criteria who received MWA or RES between 2002 and 2017. Researchers compared five-year overall survival (OS) and recurrence-free survival (RFS) using both propensity-score matching (PSM) and inverse-probability-of-treatment-weighting (IPW) analysis and investigated the prognostic factors with multivariate Cox analysis. READ MORE
Practical Radiation Oncology
The objective of this research was to elucidate the impact on the prognosis, including the survival prognosis, of proton beam irradiation of an anatomical subsegment of the liver (ASPT) for the treatment of hepatocellular carcinoma (HCC). A total of 110 patients who were diagnosed with HCC were analyzed in this retrospective study. Definitive proton beam therapy was delivered at a dose of 76 Gy in 20 fractions between January 2008 and December 2015. READ MORE
Immunology Letters
Recently, clinical studies using anti-immune checkpoint molecule antibodies have been successful in solid tumors, such as melanoma and non-small cell lung cancers. However, pancreatic cancers are still intractable and difficult to treat once recurrence or metastasis occurs; thus, novel combined use of immune checkpoint blockade (ICB) with molecular targeted drugs is considered a therapeutic option. READ MORE
Future Medicine
This study aimed to benchmark overall survival (OS) and time to radiological progression (TTP) of patients enrolled in randomized controlled trials (RCTs) assessing sorafenib in advanced hepatocellular carcinoma using individual participant survival data, and to meta-analyze prognostic factors for OS and TTP. RCTs were identified through literature search until December 2018. Individual participant survival was reconstructed with an algorithm from published Kaplan–Meier curves. READ MORE |
| Cryotherapy is a minimally invasive treatment primarily for kidney, lung, and prostate cancers as well as a palliative treatment for bone pain. It has been used since the 19th Century(see history below), but advancements continue to be made every year. Read more |
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